Endocrine Abstracts

Introduction: Current NICE guidelines recommend that children and young people with Type 1 Diabetes Mellitus (T1DM) should aim for a target HbA1c ≤48 mmol/mol (6.5%) to reduce the risk of long-term complications. The National Paediatric Diabetes Audit (NPDA) shows that the number of young people under the paediatric diabetes service with HbA1c >75 mmol/mol at this District General Hospital has been consistently and significantly above both the North West and national ave...

Introduction: Majority of patients with neuroendocrine tumors (NET) harbor hepatic metastases at presentation, posing therapeutic challenge. Multiple liver-directed treatment modalities have been employed with variable success. Herein is presented successful outcome in a patient whose recurrent metastatic liver metastases from NET was managed using multidisciplinary approach.Case report: We present long-term18-years course of a patient with liver metasta...

Transsphenoidal surgery is the first-line treatment for non-functioning pituitary macroadenomas (NFPAs) causing pressure symptoms. However, the approach to asymptomatic NFPAs is unclear due to the limited data on their natural progression. This study retrospectively analysed data from patients with NFPAs who underwent conservative management for at least six months. The study screened 175 individuals treated at the National Neurosurgery/Pituitary Centre at Beaumont Hospital be...

Background: Myxoedema coma although uncommon can be life-threatening in patients who are poorly compliant with levothyroxine replacement. Some of the precipitating factors include intercurrent respiratory infection, use of sedatives, and electrolyte imbalance such as hyponatremia(Wiersinga 2018). A 73-year-old man presented to the Hospital with face and tongue swelling, shortness of breath, and type 2 respiratory failure. His past medical history includes hypothyroidism, Obstr...